EP0471796A4 - Stably transformed eucaryotic cells comprising a foreign transcribable dna under the control of a pol iii promoter - Google Patents
Stably transformed eucaryotic cells comprising a foreign transcribable dna under the control of a pol iii promoterInfo
- Publication number
- EP0471796A4 EP0471796A4 EP19900909233 EP90909233A EP0471796A4 EP 0471796 A4 EP0471796 A4 EP 0471796A4 EP 19900909233 EP19900909233 EP 19900909233 EP 90909233 A EP90909233 A EP 90909233A EP 0471796 A4 EP0471796 A4 EP 0471796A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- control
- stably transformed
- pol iii
- iii promoter
- dna under
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
- C12N15/1132—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses against retroviridae, e.g. HIV
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/027—New breeds of vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/13—Decoys
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35417189A | 1989-05-10 | 1989-05-10 | |
US354171 | 1989-05-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0471796A1 EP0471796A1 (fr) | 1992-02-26 |
EP0471796A4 true EP0471796A4 (en) | 1993-05-05 |
Family
ID=23392147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19900909233 Withdrawn EP0471796A4 (en) | 1989-05-10 | 1990-05-10 | Stably transformed eucaryotic cells comprising a foreign transcribable dna under the control of a pol iii promoter |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0471796A4 (fr) |
JP (1) | JPH04505261A (fr) |
CA (1) | CA2055435A1 (fr) |
WO (1) | WO1990013641A1 (fr) |
Families Citing this family (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6251675B1 (en) | 1989-05-25 | 2001-06-26 | Duke University | Methods utilizing mutant rev genes encoding transdominant repressors of HIV replication |
US5871958A (en) * | 1989-05-25 | 1999-02-16 | Duke University | Mutant rev genes encoding transdominant repressors of HIV replication |
ATE286971T1 (de) | 1991-01-21 | 2005-01-15 | Elan Pharm Inc | Prüfung und modell für alzheimers-krankheit |
DE4225094A1 (de) * | 1992-04-28 | 1993-11-04 | Frank Andreas Harald Meyer | Medikament zur gentherapeutischen behandlung von menschen, tieren und pflanzen, insbesondere zur blockierung der virenvermehrung und der tumorgene sowie verfahren zur herstellung des medikaments |
US6469158B1 (en) * | 1992-05-14 | 2002-10-22 | Ribozyme Pharmaceuticals, Incorporated | Synthesis, deprotection, analysis and purification of RNA and ribozymes |
US5686599A (en) * | 1992-05-14 | 1997-11-11 | Ribozyme Pharmaceuticals, Inc. | Synthesis, deprotection, analysis and purification of RNA and ribozymes |
US5804683A (en) * | 1992-05-14 | 1998-09-08 | Ribozyme Pharmaceuticals, Inc. | Deprotection of RNA with alkylamine |
US5977343A (en) | 1992-05-14 | 1999-11-02 | Ribozyme Pharmaceuticals, Inc. | Synthesis, deprotection, analysis and purification of RNA and ribozymes |
JPH06509719A (ja) * | 1992-05-27 | 1994-11-02 | シティ・オブ・ホープ | キメラtRNALYS−リボザイム分子 |
US5583035A (en) * | 1992-12-07 | 1996-12-10 | Bayer Aktiengesellschaft | HIV antisense expression vectors |
AU5961994A (en) * | 1993-01-22 | 1994-08-15 | University Research Corporation | Localization of therapeutic agents |
CN1127527A (zh) * | 1993-05-17 | 1996-07-24 | 加利福尼亚大学董事会 | 人免疫缺陷型病毒感染和艾滋病的核酶基因治疗方法 |
CA2183154A1 (fr) * | 1994-02-14 | 1995-08-17 | Nicholas John Deacon | Souches non pathogenes de vih-1 |
US6015661A (en) * | 1994-02-14 | 2000-01-18 | The Macfarlane Burnet Centre For Medical Research Limited | Methods for the detection of non-pathogenic HIV-1 strains containing deletions in the Nef coding region and U3 region of the LTR |
US5902880A (en) * | 1994-08-19 | 1999-05-11 | Ribozyme Pharmaceuticals, Inc. | RNA polymerase III-based expression of therapeutic RNAs |
US7083979B1 (en) | 1994-03-25 | 2006-08-01 | Indiana University Foundation | Methods for enhanced retroviral-mediated gene transfer |
AU2133695A (en) * | 1994-04-06 | 1995-10-30 | Sadna Joshi-Sukhwal | Inhibition of hiv-1 multiplication in mammalian cells |
US6146886A (en) | 1994-08-19 | 2000-11-14 | Ribozyme Pharmaceuticals, Inc. | RNA polymerase III-based expression of therapeutic RNAs |
NZ311982A (en) | 1995-06-29 | 1999-08-30 | Immunex Corp | Tnf related apoptosis inducing ligand (trail), a method for producing them and associated antibodies |
JP4365456B2 (ja) | 1995-09-29 | 2009-11-18 | インディアナ・ユニバーシティ・リサーチ・アンド・テクノロジー・コーポレーション | ウイルス及び細胞結合部位を持つ分子を用いたウイルス媒介性dna導入を増強する方法 |
US6776986B1 (en) | 1996-06-06 | 2004-08-17 | Novartis Ag | Inhibition of HIV-1 replication by antisense RNA expression |
US5955644A (en) * | 1996-08-08 | 1999-09-21 | M.D. Anderson Cancer Center | Ku deficient cells and non-human transgenic animals |
US6057489A (en) * | 1996-09-12 | 2000-05-02 | M.D. Anderson Cancer Center | MmRad51-deficient cells and transgenic mice |
US6384203B1 (en) | 1999-05-12 | 2002-05-07 | Immunex Corporation | Family of immunoregulators designated leukocyte immunoglobulin-like receptors (LIR) |
EP1865061A3 (fr) | 1998-05-15 | 2007-12-19 | Genentech, Inc. | Polypeptides allogéniques IL-17 et utilisations thérapeutiques |
AU740405B2 (en) | 1998-05-15 | 2001-11-01 | Genentech Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
EP3112468A1 (fr) | 1998-05-15 | 2017-01-04 | Genentech, Inc. | Polypeptides allogéniques il-17 et utilisations thérapeutiques |
US20020172678A1 (en) | 2000-06-23 | 2002-11-21 | Napoleone Ferrara | EG-VEGF nucleic acids and polypeptides and methods of use |
ES2263285T3 (es) | 1998-08-21 | 2006-12-01 | Immunex Corporation | Adn y polipeptidos de la il-1 epsilon humana. |
EP1978029A3 (fr) | 1999-06-15 | 2008-10-15 | Genentech, Inc. | Polypeptides sécrétés et transmembranaires, et acides nucléiques les codant |
MXPA02003897A (es) | 1999-10-20 | 2002-12-13 | Genentech Inc | Modulacion de la diferenciacion de celulas t para el tratamiento de enfermedades mediadas por las celulas t auxiliares. |
EP1690872A3 (fr) | 1999-12-01 | 2006-08-23 | Genentech, Inc. | Composition et procédés de diagnostic de tumeurs |
DK1897945T3 (da) | 1999-12-23 | 2012-05-07 | Genentech Inc | IL-17 homologe polypeptider og terapeutiske anvendelser deraf. |
IL150676A0 (en) | 2000-01-13 | 2003-02-12 | Genentech Inc | NOVEL STRa6 POLYPEPTIDES |
US6740520B2 (en) | 2000-03-21 | 2004-05-25 | Genentech, Inc. | Cytokine receptor and nucleic acids encoding the same |
EP1757618A3 (fr) | 2000-03-22 | 2007-05-23 | Curagen Corporation | Proteines associées a l'angiogenese et acides nucleiques codant pour les dites proteines |
EP1944317A3 (fr) | 2000-09-01 | 2008-09-17 | Genentech, Inc. | Polypeptides sécrétés et transmembranaires, et acides nucléiques les codant |
EP1434778A4 (fr) | 2001-05-31 | 2005-07-13 | Medarex Inc | Cytotoxines, promedicaments, lieurs et stabilisateurs utiles pour ceux-ci |
US20070160576A1 (en) | 2001-06-05 | 2007-07-12 | Genentech, Inc. | IL-17A/F heterologous polypeptides and therapeutic uses thereof |
DK2000545T3 (da) | 2001-06-20 | 2011-11-28 | Genentech Inc | Sammensætninger og fremgangsmåder til diagnose og behandling af lunge-tumor |
EP2174953A1 (fr) | 2001-09-18 | 2010-04-14 | Genentech, Inc. | Compositions et procédés pour le traitement et le diagnostic d'une tumeur |
AU2002367318B2 (en) | 2002-01-02 | 2007-07-12 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
AU2003213271B2 (en) | 2002-02-25 | 2009-07-16 | Genentech, Inc. | Novel type-1 cytokine receptor GLM-R |
JP2005536190A (ja) | 2002-04-16 | 2005-12-02 | ジェネンテック・インコーポレーテッド | 腫瘍の診断と治療のための組成物と方法 |
CA2486252C (fr) | 2002-06-07 | 2012-07-24 | Genentech, Inc. | Procedes de criblage d'agents modulant le developpement du carcinome hepatocellulaire |
EP2784084B2 (fr) | 2003-07-08 | 2023-10-04 | Novartis Pharma AG | Polypeptides hétérologues IL-17 A/F et utilisations thérapeutiques associées |
ES2493016T3 (es) | 2003-11-17 | 2014-09-11 | Genentech, Inc. | Composiciones que comprenden anticuerpos contra CD79b conjugados a un agente inhibidor del crecimiento o un agente citotóxico y procedimientos para el tratamiento de tumores de origen hematopoyético |
AU2006223498A1 (en) | 2005-03-10 | 2006-09-21 | Genentech, Inc. | Methods and compositions for modulating vascular integrity |
EP1871163A2 (fr) | 2005-06-06 | 2008-01-02 | Genentech, Inc. | Nouvelles interruptions geniques, compositions et methodes associees |
WO2007021423A2 (fr) | 2005-08-15 | 2007-02-22 | Genentech, Inc. | Disruptions et compositions geniques et procedes associes |
CN101312748A (zh) | 2005-09-26 | 2008-11-26 | 梅达莱克斯公司 | 抗体-药物轭合物和使用方法 |
JP2009516514A (ja) | 2005-11-21 | 2009-04-23 | ジェネンテック・インコーポレーテッド | 新規遺伝子破壊、それらに関する組成物および方法 |
CA2638821A1 (fr) | 2006-02-17 | 2007-10-11 | Genentech, Inc. | Nouvelles disruption geniques, compositions et procedes associes |
EP2614839A3 (fr) | 2006-04-05 | 2015-01-28 | Genentech, Inc. | Méthode d'utilisation du BOC/CDO pour moduler l'émission des signaux du hedgehog |
EP2010662A2 (fr) | 2006-04-19 | 2009-01-07 | Genentech, Inc. | Nouvelles disruptions génétiques, compositions et procédés les concernant |
EP3255144A1 (fr) | 2007-08-10 | 2017-12-13 | E. R. Squibb & Sons, L.L.C. | Construction de type recombineering pour la préparation de souris transgeniques capables de produire des immunoglobulines humaines. |
US8324182B2 (en) | 2008-02-15 | 2012-12-04 | Tufts University | Humanized model of membrane attack complex (MAC) formation on murine retina and compositions, kits and methods for treatment of macular degeneration |
US8877896B2 (en) | 2008-02-15 | 2014-11-04 | Tufts University | Compositions, methods and kits for modeling, diagnosing, and treating complement disorders |
CA2772715C (fr) | 2009-09-02 | 2019-03-26 | Genentech, Inc. | Mutant smoothened et ses methodes d'utilisation |
WO2011047267A1 (fr) | 2009-10-15 | 2011-04-21 | Genentech, Inc. | Facteurs de croissance chimériques des fibroblastes avec spécificité de récepteur modifiée |
CN102711826B (zh) | 2009-10-22 | 2017-03-29 | 霍夫曼-拉罗奇有限公司 | 用于调控巨噬细胞刺激性蛋白的hepsin活化的方法和组合物 |
CA2781887C (fr) | 2009-11-30 | 2018-03-27 | Genentech, Inc. | Compositions et procedes destines a diagnostiquer et a traiter des tumeurs |
EP2538981B1 (fr) | 2010-02-23 | 2017-12-20 | F. Hoffmann-La Roche AG | Compositions et procedes de diagnostic et traitement de tumeurs |
MA34291B1 (fr) | 2010-05-03 | 2013-06-01 | Genentech Inc | Compositions et méthodes de diagnostic et de traitement d'une tumeur |
CA2843684A1 (fr) | 2010-08-13 | 2012-02-16 | Tufts University | Compositions, trousses et methodes de traitement de la degenerescence maculaire au moyen de la proteine cd59 soluble independante de la membrane |
US8481680B2 (en) | 2010-10-05 | 2013-07-09 | Genentech, Inc. | Mutant smoothened and methods of using the same |
WO2015116902A1 (fr) | 2014-01-31 | 2015-08-06 | Genentech, Inc. | Récepteurs couplés aux protéines g dans la signalisation hedgehog |
EP3102197B1 (fr) | 2014-02-04 | 2018-08-29 | Genentech, Inc. | Mutant smoothened et méthodes d'utilisation de celui-ci |
EP3186269B1 (fr) | 2014-08-28 | 2021-03-10 | Tufts University | Compositions, procédés et kits pour le traitement des troubles liés au complément |
US10330683B2 (en) | 2015-02-04 | 2019-06-25 | Genentech, Inc. | Mutant smoothened and methods of using the same |
AU2017213826A1 (en) | 2016-02-04 | 2018-08-23 | Curis, Inc. | Mutant smoothened and methods of using the same |
US20210052743A1 (en) | 2018-02-12 | 2021-02-25 | Trustees Of Tufts College | Cd59 for inhibiting inflammasome activation |
WO2023089564A1 (fr) | 2021-11-19 | 2023-05-25 | Janssen Biotech, Inc. | Méthode de traitement d'une atrophie géographique avec un vecteur de thérapie génique exprimant cd59 soluble |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0387775A1 (fr) * | 1989-03-16 | 1990-09-19 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Unité génétique pour inhiber la fonction d'ARN |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4497796A (en) * | 1980-03-26 | 1985-02-05 | The Regents Of The University Of California | Gene transfer in intact mammals |
-
1990
- 1990-05-10 CA CA002055435A patent/CA2055435A1/fr not_active Abandoned
- 1990-05-10 EP EP19900909233 patent/EP0471796A4/en not_active Withdrawn
- 1990-05-10 JP JP2508724A patent/JPH04505261A/ja active Pending
- 1990-05-10 WO PCT/US1990/002656 patent/WO1990013641A1/fr not_active Application Discontinuation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0387775A1 (fr) * | 1989-03-16 | 1990-09-19 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Unité génétique pour inhiber la fonction d'ARN |
Non-Patent Citations (1)
Title |
---|
See also references of WO9013641A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO1990013641A1 (fr) | 1990-11-15 |
JPH04505261A (ja) | 1992-09-17 |
CA2055435A1 (fr) | 1990-11-11 |
EP0471796A1 (fr) | 1992-02-26 |
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Legal Events
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
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17P | Request for examination filed |
Effective date: 19911210 |
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AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB IT LI LU NL SE |
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Effective date: 19930316 |
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Effective date: 19931026 |
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Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 19980730 |