WO2007085568A1

WO2007085568A1 - Use of n,n-dimethyldecanamide in cosmetic preparations

Info

Publication number: WO2007085568A1
Application number: PCT/EP2007/050531
Authority: WO
Inventors: Valerie Andre; Volker Wendel
Original assignee: Basf Se
Priority date: 2006-01-27
Filing date: 2007-01-19
Publication date: 2007-08-02
Also published as: EP1986597A1

Abstract

The invention relates to cosmetic preparations that are suitable for protecting human skin or human hair from damage caused by sunlight, especially UV-B radiation (280 to 320 nm) and UV-A radiation (> 320 nm), and contain specific amido compounds, e.g. dimethyldecanamide.

Description

Use of N, N-dimethyldecanamide in cosmetic preparations

description

The invention relates to dermocosmetics suitable for the protection of human skin or human hair from damage by sunlight, in particular by UV-B (280 to 320 nm) and UV-A radiation (> 320 nm).

Human skin is subject to certain aging processes that are partly due to intrinsic processes (chronoaging) and partly due to exogenous factors (environmental, such as photoaging). In addition, transient or persistent changes in the appearance of the skin may occur, such as acne, oily or dry skin, keratoses, rosaceae, photosensitive, inflammatory, erythematous, allergic or autoimmune reactions such as dermatoses and photodermatoses.

The exogenous factors include, in particular, sunlight or artificial radiation sources with a comparable spectrum as well as free-radical or ionic compounds which can be formed by the radiation. These factors include cigarette smoke and the reactive compounds it contains, such as ozone, free radicals, singlet oxygen and other reactive oxygen or nitrogen compounds.

The total ozone in Germany has fallen by almost 10% since 1968, or by about 3% per decade. The UV radiation has increased by about 15% in the same period.

Sunburn-inducing UV-B radiation around 300 nm wavelength has the greatest cancer efficacy. It increases the risk of developing so-called non-melanoma skin cancer (spinal or squamous cell carcinoma or basal cell carcinoma or basal cell carcinoma). The risk for tumors increases with the number of sunburns. In particular, the UV exposure in the first ten years of life (sunburn in children) affects the risk of cancer.

According to estimates by the WHO, two million people worldwide suffer from basal cell and squamous cell carcinoma every year and around 200,000 from melanoma. In Germany, the number of new cases of skin cancer is around 120,000, of which 7 percent is attributable to melanoma. Every year 1,600 deaths in Germany are attributable to melanoma or non-melanoma skin cancer. (Doctors newspaper, 17.05.2000, www.aerztezeitung.de)

In view of the above-mentioned developments, the provision of the mocosmetic products with improved, more effective or optimized protection of human skin from the damaging effects of UV-A and UV-B radiation of great importance. It is particularly desirable to provide dermocosmetics that achieve the desired effect with the lowest possible amount of the individual components. The specific extinction of light stabilizers play a role as well as the stability of the emulsions prepared with them, their toxicological harmlessness and their solubility in the carriers used (eg cosmetic oils). Some of the light stabilizers used to date are characterized by good extinction properties, but the low solubility of these substances prevents their optimal use. For example, the Uvinul®T50 UV filter substance marketed by BASF Aktiengesellschaft is characterized by excellent UV absorption properties, but this UV filter can only be dissolved to a limited extent in cosmetic oils, which limits the protection factor to be achieved by this filter. Although it has been proposed in the patent applications DE 19633012 and DE 19635057 substances which have a positive effect on the solubility of Uvinul®T50 in cosmetic preparations, however, the results are not satisfactory in view of the sun protection factors achieved therewith. Further, the poorly soluble UV filter substances tend to recrystallize with temperature variations and thereby render the product ineffective.

Thus, there is a growing demand for suitable solvents, solvent mediators, emulsifiers or stabilizers which can be used in sunscreens.

It was therefore an object of the present invention to provide dermocosmetics which are distinguished by an increased concentration of sparingly soluble UV filter substances. It was another object of the present invention to identify substances that have a positive influence on the solubility of poorly soluble UV filter substances. In addition, it was an object of the present invention to identify substances, by the use of which an increase in the sun protection factor of a dermoskometischen preparation can be increased. A further object according to the invention was the identification of a substance which positively influences the recrystallization of sparingly soluble UV filter substances. It was also an object of this invention to provide dermocosmetics that achieve acceptable light protection values (SPF, sun protection factor) at low concentrations of poorly soluble UV filters, and thus at low production costs.

Surprisingly, it has been found that these objects could be achieved by using compounds according to the general formula I in dermocosmetics suitable for protection against UV radiation. definitions

"Dermocosmetics" or "dermocosmetics" describes skin-cosmetic, hair-cosmetic, dermatological, hygienic or pharmaceutical agents, preparations and / or formulations for topical application to skin or hair, suitable (i) for the prevention of damage to human skin and / or human hair, ( (ii) to treat damage to human skin and / or human hair that has already occurred, (iii) to care for human skin and / or human hair, (iv) to improve skin feel (sensory properties). Explicitly included are cosmetics for decorative cosmetics. Also included are skin care compositions in which the pharmaceutically dermatological application is achieved taking into account cosmetic considerations. Such agents or preparations are used for the support, prevention and treatment of skin diseases and can develop a biological effect in addition to the cosmetic effect. The dermocosmetics according to the invention are particularly preferably preparations for protecting the skin from damage by sunlight, in particular by UV-B (280 to 320 nm) and UV-A radiation (> 320 nm). Dermocosmetics contain in a cosmetically acceptable medium suitable auxiliaries and additives, which are chosen with regard to the specific field of application. Such auxiliaries and additives are familiar to the person skilled in the art and can be used e.g. Handbooks of cosmetics, such as Schrader, bases and formulations of cosmetics, Hüthig Verlag, Heidelberg, 1989, ISBN 3-7785-1491-1, or Umbach, cosmetics: development, production and application of cosmetic products, 2nd extended edition, 1995, Georg Thieme Verlag, ISBN 3 13 712 602 9, are taken.

"Dermocosmetics suitable for protecting human skin or hair against UV radiation" comprise one or more organic and / or inorganic light stabilizers or UV filters in combination with one or more of the following substances: emulsifiers, surfactants, preservatives, par greases, thickeners, hair polymers, hair and skin conditioners, graft polymers, water-soluble or dispersible silicone-containing polymers, gelling agents, conditioners, colorants, tinting agents, tanning agents, dyes, pigments, bodying agents, moisturizers, restockers, collagen, protein hydrolysates, lipids, and / or The active compounds can also be used in encapsulated form as described in the patents / patent applications EP 00974775 B1, DE 231 1 712, EP 0278 878, DE 1999 47147, EP 0706822B1 and WO 98/16621, the contents of which are expressly incorporated herein by reference Be included in the cosmetic preparations.

"Dermocosmetic agents" or "dermocosmetically active agents" in the context of the present invention are the active ingredients present in dermocosmetics according to the definition given above which (i) for the prevention of damage to human skin and / or human hair, (ii) for the treatment of damage already suffered to human skin and / or human hair, (iii) (iv) to improve the skin feel (sensory properties) and (v) to decorate or enhance the appearance of the human skin and / or human hair. Such agents are selected, for example, from the group of natural or synthetic polymers, pigments, humectants, oils, waxes, proteins, enzymes, minerals, vitamins, sunscreens, dyes, fragrances, antioxidants, Peroxydzersetzer and preservatives and pharmaceutical agents to support, prevent and Treatment of skin diseases are used and have a healing, damage preventive, regenerating or general skin condition improving biological effect.

"Cosmetically acceptable medium" is to be understood broadly and means substances suitable for the preparation of cosmetic or dermocosmetic preparations and mixtures thereof.

"Cosmetically-compatible substances" do not cause irritation or damage on contact with human or animal dermal tissue or hair and are incompatible with other substances, and have low allergenic potential and are approved by the state regulatory authorities for use in cosmetic preparations These substances are familiar to the person skilled in the art and can be found, for example, in the handbooks of cosmetics, for example Schrader, bases and formulations of cosmetics, Hüthig Verlag, Heidelberg, 1989, ISBN 3-7785-1491-1.

Recrystallization in the sense of the present invention means a reduced tendency of a poorly soluble UV filter in a given dermocosmetic preparation to recrystallise depending on the concentration of the filter or the temperature of the preparation. In this case, a reduced tendency means a reduction in the temperature tolerated by the UV filter in a preparation at which recrystallization sets in (recrystallization temperature). This is preferably a reduction of the temperature by 1 ° C, or 2 ° C, or 3 ° C, or 4 ° C, preferably 5 ° C, or 6 ° C, or 7 ° C, or 8 ° C, or 9 ° C, more preferably 10 ⁰ C, or 1 1 ° C, or 12 ° C, or 13 ° C, or 14 ° C, most preferably 15 ° C, or more. Further, a reduced tendency means an increase in the maximum concentration of a UV filter dissolved in a preparation at a constant temperature at which recrystallization starts (recrystallization concentration). This is preferably an increase in the concentration of 1, or 2, or 3, or 4, preferably 5, or 6 or 7, or 8, or 9, particularly preferably 10, or 1 1, or 12, or 13, or 14, most preferably 15 weight percent or more, based on the total weight of the preparation

"Sparingly soluble organic UV filters" in the context of the present invention means organic UV filters with a solubility in Cetiol® CC of less than 25%, 26%, 27%, 28 or 30%, preferably less than 31%, 32%, 33%, 34% or 35%, more preferably less than 36%, 37%, 38%, 39% or 40% at 20 ° C and a test time of 24 hours. The presence of crystals is detected by means of an optical probe.

"Increase of the sun protection factor" or sun protection factor (SPF) - also SPF (sun protection factor) of a dermatocritic suitable for the protection of the skin from UV radiation means an increase of the sun protection factor determined by the COLI PA method familiar to the expert increasing the SPF at least 1-5, preferably 5-10, more preferably 10-15, or more units of a SPF N, N-Dimethyldecanamid contain Denden Dermokosmetikums compared to the identical composition without Dermokosmetikum N ₁ N- Dimethyldecanamid.

Increasing the solubility for the purposes of the present invention means an increase in the concentration of a given poorly soluble UV filter in a dermocromic by 2, or 4, or 6, or 8, preferably 10, or 11, or 12, or 13, or 14 , more preferably 15, or 16, or 17, or 18, or 19, most preferably 20, or more percent at room temperature.

Detailed description of the invention

In a first embodiment, the invention accordingly relates to a dermocosmetic suitable for protection against UV radiation containing

a) a compound of general formula I,

O

Formula I 1 1 OH ₃ (CH ₂ ) _n -CN (CH ₃ ) ₂

where "n" corresponds to an integer from 2 to 12, and b) at least one sparingly soluble organic UV filter.

In a particularly preferred embodiment, the sparingly soluble organic UV filter mentioned under b) is a triazine derivative, diaryl butadiene derivative, hydroxybenzophenone derivative and / or methylene bisbenzotriazolyl tetramethylbutylphenol derivative.

In the triazine derivatives of the compounds 2,4,6-tris [anilino (- hexyloxy p-carbo-2 ^{^'-ethyl-1')]} - are 1, 3,5-triazine, dioctyl, Bis-Ethylhexyloxyphenol-methoxy- phenyltriazine, 2,4,6-tris (diethyl-4 ^{'-amino-benzalmalonates)} -s-triazine, 2,4,6-tris (dimethyl- 4 ^{'-amino-benzalmalonates-s-triazine,} 2,4,6-tris (diiso-propyl-4-aminobenzal-malonate) -s-triazine, 2,4,6-tris ^[3' benzotriazole-2-yl ) -2 ^{^'hydroxy-5'} methyl) phenyl-amino] -s-triazine and 2, 4, 6-tris [3 ^{'benzotriazol-2-yl)} ^-2' -hydroxy-5 ^{'-tert-octyl)} phenyl-amino] -s-triazine preferred. Particularly preferred are the triazine derivative is 2,4,6-tris [anilino (p-carbo-2 ^{^'-ethyl-1'} -hexyloxy)] - 1, 3,5-triazine (Uvinul®T150, BASF Aktiengesellschaft) Dioctylbutamidotriazone (UV-Sorb-HEB®, 3V Sigma) and bis-ethylhexyloxyphenolmethoxyphenyltriazine (anisotriazines or Tinosorb®s, Ciba-Geigy). Most preferably, the compounds triazine 2,4,6-tris- [anilino- (p-carbo-2 ^{^'-ethyl-1'} -hexyloxy)] are - 1, 3,5-triazine (Uvinul ®T150, BASF Aktiengesellschaft, ) Dioctylbutamido-triazone (UV-Sorb-HEB®,

3V Sigma). Further triazine derivatives can be found in the patent applications EP-A 0796851, EP-A 0087098 and EP-A 0850935.

In the case of the diarylbutadiene derivatives, the 4,4'-diarylbutadienes of the formula II

H C00R4

^ \ "\ C00R5

I,

H

Formula Il

where R ⁴ and R ⁵ independently of one another are hydrogen, C 1 -C 20 -alkyl, C 3 -C 10 -cycloalkyl or C 3 -C 10 -cycloalkenyl, are preferred. Particularly preferred are the compound 1, 1-dicarboxy (2 ^{^'2'} -dimethyl) is -4-4-diphenylbutadiene. The stated 4,4'-diarylbutadienes are known as such and their structure and preparation are described in the patent applications EP 0967200 and EP 916 335, the contents of which are hereby incorporated by reference.

In the case of the hydroxybenzophenones, the compounds of the general formula III,

formula

where R ¹ and R ² independently of one another are hydrogen, C 1 -C 20 -alkyl, C 3 -C 10 -cycloalkyl or C 3 -C 10 -cycloalkenyl, where the substituents R ¹ and R ² together with the nitrogen atom to which they are attached form a 5 - or 6-ring and R ^{3 is} a Ci-C2o-alkyl, preferably. Particularly preferred 2- (4-N, N-diethylamino-2-hydroxybenzoyl) benzoic acid (Uvinul® A Plus, BASF Aktiengesellschaft). Further examples of hydroxybenzophenones and their preparation can be found in the German Patent Application DE-A 1 1917906, the content of which is hereby expressly incorporated by reference.

In the case of the methylene-bis-benzotriazolyl-tetramethylbutylphenol derivatives, 2,2-methylenebis [6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) phenol] (Tinosorb®M, Ciba) Geigy) preferred. These compounds are also described in FR 2440933, the contents of which are hereby incorporated by reference.

Another preferred subject matter of the invention relates to dermocosmetics comprising a compound according to formula 1, preferably N, N-dimethyldecanamide, with a sparingly soluble organic UV filter, where this is a triazine derivative, diarylbutadiene derivative, hydroxybenzophenone derivative and / or methylene bis-benzotriazolyl tetramethylbutylphenolderivat is in dermocosmetics. Particular preference is given to using the triazine, diarylbutadiene, hydroxybenzophenone and / or methylene-bis-benzotriazolyl-tetramethylbutylphenol derivatives already described above and mentioned as being preferred. 1, 3,5-triazine (Uvinul ®-T150, BASF Aktienge - Very particularly preferred are the compounds 2,4,6-tris [anilino (p-carbo-2 ^{^'-ethyl-1'} -hexyloxy)] are - roped) Dioctylbutamido-triazone (UV-Sorb-HEB®, 3V Sigma), bis-ethylhexyloxyphenol methoxyphenyltriazin (Anisotriazin or Tinosorb®S, Ciba-Geigy), 1, 1-dicarboxy (2 ^{^'2'} -dimethyl) -4 4-diphenylbutadiene, 2- (4-N, N-diethylamino-2-hydroxybenzoyl) benzoic acid (Uvinul® A Plus, BASF Aktiengesellschaft) and 2,2-methylenebis [6- (2H-benzotriazol-2-yl) -] 4- (1,1,3,3-tetramethylbutyl) phenol] (Tinosorb®M, Ciba-Geigy).

In a particularly preferred embodiment, the dermocosmetics according to the invention contain mixtures of the abovementioned sparingly soluble UV filters.

Particularly preferred mixtures contain combinations of

N, N-Dimethyldecanamid, 2,4,6-tris [anilino (p-carbo-2 ^{^'-ethyl-1'} -hexyloxy)] - 1, 3,5-triazine

(Uvinul® -T150, BASF Aktiengesellschaft) and 2- (4-N, N-diethylamino-2-hydroxybenzoyl) benzoic acid (Uvinul® A Plus, BASF Aktiengesellschaft) [combination A], or

N, N-dimethyldecanamide, 2- (4-N, N-diethylamino-2-hydroxybenzoyl) benzoic acid (Uvinul® A Plus, BASF Aktiengesellschaft) and dioctylbutamido-triazone (UV-Sorb-HEB®, 3V Sigma) [ combination B], or N, N-Dimethyldecanamid, 2,4,6-tris [anilino (p-carbo-2 ^{^'-ethyl-1'} -hexyloxy)] - 1, 3,5-triazine (Uvinul © - T150, BASF Aktiengesellschaft) and bis-ethylhexyloxyphenol-methoxyphenyltriazine (anisotriazine or Tinosorb®S, Ciba-Geigy) [combination C], or N, N-dimethyldecanamide, dioctylbutamido-triazone (UV-Sorb-HEB®, 3V Sigma) and bis-ethylhexyloxyphenol-methoxyphenyltriazine (anisotriazines or Tinosorb®S, Ciba-Geigy) [combination D], or

N, N-dimethyldecanamide, 2- (4-N, N-diethylamino-2-hydroxybenzoyl) benzoic acid (Uvinul® A Plus, BASF Aktiengesellschaft), dioctylbutamido-triazone (UV-Sorb-HEB®, 3V Sigma) and Bis-ethylhexyloxyphenol-methoxyphenyltriazine (anisotriazine or Tinosorb®S, Ciba-Geigy) [combination E], or

N, N-Dimethyldecanamid, 2,4,6-tris [anilino (p-carbo-2 ^{^'-ethyl-1'} -hexyloxy)] - 1, 3,5-triazine (Uvinul © -T150, BASF Aktiengesellschaft) , 2- (4-N, N-diethylamino-2-hydroxybenzoyl) benzoic acid (Uvinul®A Plus, BASF Aktiengesellschaft), and bis-ethylhexyloxyphenolmethoxyphenyltriazine (anisotriazine or Tinosorb®S, Ciba-Geigy), [combination F]

In the above combinations A-F is

2- (4-N, N-diethylamino-2-hydroxybenzoyl) benzoic acid (Uvinul® A Plus, BASF Aktiengesellschaft) in a concentration of 0.1 to 10%,

2,4,6-tris- [anilino- (p-carbo-2 ^{^'-ethyl-1'} -hexyloxy)] - 1, 3,5-triazine (Uvinul © -T150, BASF Aktiengesellschaft) in a concentration of 0, 1 to 5%, bis-ethylhexyloxyphenol-methoxyphenyltriazine (anisotriazine or Tinosorb®S, Ciba-Geigy) in a concentration of 0.1 to 5%, and

Dioctylbutamido-triazone (UV-Sorb-HEB®, 3V Sigma) used in a concentration of 0.1 to 5% by weight based on the total weight of the dermocosmetic.

In a further embodiment of the invention, the number "n" in the compound (a) according to the general formula I is an integer from 3 to 11, preferably 4 to 10, more preferably 5 to 9, most preferably 6 to 8 . In a further preferred embodiment, the compound is N ₁ N- Dimethyldecanamid (CAS no. 14433-76-2), very particularly preferably Spectrasolv DMDA (Jiangsu Feixang Chemicals).

In addition to the combination of the compounds mentioned under (a) and (b), further ultraviolet-absorbing substances may be present in the dermocosmetic, but at least effective amounts of the compounds mentioned under (a) and (b) should be included in the sunscreen preparations. Effective amounts of the compounds mentioned under (a) and (b) are generally understood in each case to be at least 1% by weight, based on the cosmetic preparation. The particular use of the sparingly soluble organic UV filters and the compounds according to formula 1 is preferably in a concentration of 0.1 to 20, preferably 1 to 15, particularly preferably 1 to 10% by weight, based on the total weight of the agent ( Wt .-%), wherein the amounts of the compounds mentioned under (a) and (b) need not be equal. Another object of the present invention are the dermocosmetics described above which additionally contain at least one further organic or inorganic UV filter.

In the case of the inorganic UV filters, titanium dioxide, zinc oxide, iron oxide, zirconium oxide and cerium oxide are particularly preferred, and these may be present individually or in mixtures.

Particularly preferred mixtures contain combinations of:

[Combination A] plus titanium dioxide [combination G], or [combination B] plus titanium dioxide [combination H], or

[Combination C] plus titanium dioxide [combination I], or

[Combination D] plus titanium dioxide [combination J], or

[Combination E] plus titanium dioxide [combination K], or

[Combination F] plus titanium dioxide [combination L], or

[Combination A] plus zinc oxide [combination M], or

[Combination B] plus zinc oxide [combination N], or

[Combination C] plus zinc oxide [combination O], or

[Combination D] plus zinc oxide [combination P], or [combination E] plus zinc oxide [combination Q], or

[Combination F] plus zinc oxide [combination R].

In the case of the organic UV filters, the following substances are preferred: 4-aminobenzoic acid derivatives, 3- (4'-trimethylammonium) -benzylidene-bornan-2-one methylsulfate derivatives, 3,3,5-trimethylcyclohexyl-salicylate derivatives, 2 -Hydroxy-4-methoxybenzophenone derivatives, 2-phenylbenzimidazole-5-sulfonic acid derivatives and their potassium, sodium, and the like. Triethanolamine salts, 3,3 '- (1, 4-phenylenedimethine) bis (7,7-dimethyl-2-oxobicyclo [2.2.1] heptane-1-methanesulfonic acid) derivatives and their salts, 1- (4 tert-butylphenyl) -3- (4-methoxyphenyl) propane-1,3-dione derivatives, 3- (4'-sulfo) benzylidene-bornan-2-one derivatives and their salts, 2-cyano-3,3 -diphenyl-acrylic acid (2-ethylhexyl ester) derivatives, polymer of N- [2 (and 4) - (2-oxoborn-3-ylidenemethyl) benzyl] acrylamide, 4-methoxycinnamic acid 2-ethylhexyl ester derivatives , Ethoxylated ethyl 4-aminobenzoate derivatives, 4-methoxycinnamic acid isoamyl ester derivatives, 2- (2H-benzotriazol-2-yl) -4-methyl-6- (2-methyl-3- (1, 3 , 3,3-tetramethyl-1- (trimethylsilyloxy) -dililoxanyl) propyl) phenol derivatives, 3- (4'-methylbenzylidene) -DL-camphor derivatives, 3-benzylidene-camphor derivatives, 2-ethylhexyl salicylate Derivatives, 2-ethylhexyl 4-dimethyl-aminobenzoate derivatives, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid derivatives and their sodium salts, 2,2 ^' - (1,4-phenylene) bis (1 H-benzimidazole-4,6-disulfonic acid ure derivatives), 2,4-bis [4- (2-ethylhexyl-oxy) -2-hydroxy-phenyl] -6- (4-methoxyphenyl) -1, 3,5-triazine derivatives, dimethicodiethylbenzalmalonate derivatives and 2 - (- 4- (Diethlyamino) -2-hydroxyl-benzoyl-benzoic acid hexyl ester derivatives, which may be present individually or in mixtures. Particularly preferred blends contain combinations of: [combination A] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination S], or [combination B] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination T], or [combination C] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination U], or [combination D] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination V], or [combination E] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination W], or [combination F ] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination X], or

[Combination A] plus Avobenzone [combination Y], or [combination B] plus Avobenzone [combination Z], or

[Combination C] plus Avobenzone [combination A1], or

[Combination D] plus Avobenzone [combination B1], or

[Combination E] plus Avobenzone [combination C1], or

[Combination F] plus Avobenzone [combination D1] (where Avobenzone is identical to 4-t-butyl-4'-methoxy-dibenzoylmethane) or

[Combination A] plus Uvinul® N 539 (BASF Aktiengesellschaft) [combination E1], or [combination B] plus Uvinul® N 539 (BASF Aktiengesellschaft) [combination F1], or [combination C] plus Uvinul® N 539 (BASF Aktiengesellschaft ) [Combination G1], or [combination D] plus Uvinul® N 539 (BASF Aktiengesellschaft) [combination H1], or [combination E] plus Uvinul® N 539 (BASF Aktiengesellschaft) [combination 11], or [combination F] plus Uvinul® N 539 (BASF Aktiengesellschaft) [combination J1].

In a particularly preferred embodiment of the present invention, the above-described dermocosmetics additionally contain at least one further inorganic filter selected from the group consisting of titanium dioxide, zinc oxide, iron oxide, zirconium oxide and cerium oxide and an organic, besides at least one compound according to formula I and at least one sparingly soluble UV filter UV filter selected from the group comprising 4-aminobenzoic acid derivatives, 3- (4-trimethylammonium) -benzyliden-bornan-2-one-methylsulfate derivatives, 3,3,5-trimethylcyclohexyl-salicylate derivatives, 2-hydroxy-4- methoxybenzophenone derivatives, 2-phenylbenzimidazole-5-sulfonic acid derivatives and their potassium, sodium, and the like. Triethanolamine salts, 3,3 '- (1,4-phenylenedienethine) bis (7,7-dimethyl-2-oxobicyclo [2.2.1] heptane-1-methanesulfonic acid) derivatives and their salts, (4-tert-butylphenyl) -3- (4-methoxyphenyl) propane-1,3-dione derivatives, 3- (4'-sulfo) -benzylidene-bornan-2-one derivatives and their salts, 2 Cyano-3,3-diphenyl-acrylic acid (2-ethylhexyl ester) derivatives, polymer of N- [2 (and 4) - (2-oxoborn-3-ylidenemethyl) benzyl] -acrylamide, 4-methoxycinnamic acid-2 ethyl hexyl ester derivatives, ethoxylated ethyl 4-amino benzoate derivatives, 4-methoxycinnamic acid isoamyl ester derivatives, 2- (2H-benzotriazol-2-yl) -4-methyl-6- (2-methyl) 3- (1, 3,3,3-tetramethyl-1- (trimethylsilyloxy) -disiloxanyl) propyl) phenol derivatives, 3- (4'-methylbenzylidene) -DL-camphor derivatives, 3-benzylidene-camphor derivatives, Salicylic acid 2-ethylhexyl ester derivatives, 4-dimethylaminobenzoic acid 2-ethylhexyl ester derivatives, 2-hydroxy-4-methoxy-benzophenone-5-sulfonic acid derivatives and their sodium salt, 2,2 ^' - (1, 4 Phenylene) bis (1H-benzimidazole-4,6-disulfonic acid acid derivatives, 2,4-bis [4- (2-ethylhexyl-oxy) -2-hydroxyphenyl] -6- (4-methoxyphenyl) -1, 3,5-triazene derivatives, dimethicodiethylbenzalmalonate derivatives and 2 - (- 4- (diethlyamino) -2- Hydroxylbenzoyl-benzoic acid hexyl ester derivatives.

Dermocosmetics are very particularly preferably the at least one compound according to formula 1, at least one sparingly soluble UV filter, titanium dioxide and / or zinc oxide and a further organic UV filter selected from the group consisting of 2-hydroxy-4-methoxybenzophenone derivatives, 2-cyano groups. 3,3-diphenyl-acrylic acid (2-ethylhexyl) derivatives and ethoxylated-ethyl-4-amino-benzoate derivatives.

Particularly preferred blends contain combinations of: [combination G] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination K1], or [combination H] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination L1], or [combination I] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination M1], or [combination J] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination N1], or [combination K] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination 01], or [combination L ] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination P1], or

[Combination G] plus avobenzone [combination Q1], or

[Combination H] plus Avobenzone [combination R1], or

[Combination I] plus Avobenzone [combination S1], or

[Combination J] plus Avobenzone [combination T1], or

[Combination K] plus Avobenzone [combination U1], or [combination L] plus Avobenzone [combination V1], or

[Combination G] plus Uvinul® N 539 (BASF Aktiengesellschaft) [combination W1], or [combination H] plus Uvinul® N 539 (BASF Aktiengesellschaft) [combination X1], or [combination I] plus Uvinul® N 539 (BASF Aktiengesellschaft ) [Combination Y1], or [combination J] plus Uvinul® N 539 (BASF Aktiengesellschaft) [combination Z1], or [combination K] plus Uvinul® N 539 (BASF Aktiengesellschaft) [combination A2], or [combination L] plus Uvinul® N 539 (BASF Aktiengesellschaft) [combination B2], or

[Combination M] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination C2], or [combination N] plus Uvinu® MC80 (BASF Aktiengesellschaft) [combination D2], or

[Combination O] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination E2], or

[Combination P] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination F2], or

[Combination Q] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination G2], or

[Combination R] plus Uvinul® MC80 (BASF Aktiengesellschaft) [combination H2], or

[Combination M] plus avobenzone [combination 12], or [combination N] plus avobenzone [combination J2], or [combination O] plus avobenzone [combination K2], or [Combination P] plus avobenzone [combination L2], or [combination Q] plus avobenzone [combination M2], or [combination R] plus avobenzone [combination N2], or

[Combination M] plus Uvinul® N 539 (BASF Aktiengesellschaft) [combination 02], or [combination N] plus Uvinul® N 539 (BASF Aktiengesellschaft) [combination P2], or [combination O] plus Uvinul® N 539 (BASF Aktiengesellschaft ) [Combination Q2], or [combination P] plus Uvinul® N 539 (BASF Aktiengesellschaft) [combination R2], or [combination Q] plus Uvinul® N 539 (BASF Aktiengesellschaft) [combination S2], or [combination R] plus Uvinul® N 539 (BASF Aktiengesellschaft) [combination T2].

According to the invention, the above-described organic or inorganic UV filters can be present in micronized form. Examples of micronized UV filters can be found in patent applications WO-2004085412, US Pat. No. 5,340,567 and US Pat. No. 5,587,148. The contents of said patent applications are expressly incorporated by reference.

In a preferred embodiment of the invention, the dermocosmetics contain the additional organic UV filters in a concentration of 0.1 to 20, preferably 1 to 15, particularly preferably 1 to 10% by weight, based on the total weight of the composition.

In a preferred embodiment of the invention, the dermocosmetics contain the additional inorganic UV filters in a concentration of 0.1 to 50, preferably 1 to 25, particularly preferably 1 to 15% by weight, based on the total weight of the agent.

Further UV filter combinations according to the invention can be taken from the examples.

Another object of the invention relates to the use of a compound according to the general formula I in combination with at least one sparingly soluble organic UV filter in a dermocosmetic suitable for protecting the human skin or human hair against UV radiation.

In a preferred embodiment, compounds according to the general formula I are used in the dermocosmetics according to the invention, in which the number "n" for an integer from 3 to 1 1, preferably 4 to 10, particularly preferably 5 to 9, most preferably 6 to 8. In a further preferred embodiment, the compound is N, N-dimethyldecanamide (CAS No. 14433-76-2) (Spectrasolv DMDA, Jiangsu Feixang Chemicals). A further preferred subject matter of the invention relates to the combined use of a compound according to formula 1, preferably N, N-dimethyldecanamide (Spectrasolv DMDA; Jiangsu Feixang Chemicals), with a sparingly soluble organic UV filter, which comprises a triazine derivative, diarylbutadiene derivative, hydroxybenzophenone derivative. rivat and / or methylene bis-benzotriazolyl tetramethylbutylphenolderivat, in dermo-cosmetics. Very particular preference is given to using the triazine, diarylbutadiene, hydroxybenzophenone and / or methylene-bis-benzotriazolyl-tetramethylbutylphenol derivatives already described above and mentioned as being preferred. 1, 3,5-triazine (Uvinul ®-T150, BASF Aktiengesellschaft - Very particularly preferred are the compounds 2,4,6-tris [anilino ( ^'- ^ethyl-1' -hexyloxy p-carbo-2)] are ,) Dioctylbu- tamido-triazone (UV-Sorb-HEB®, 3V Sigma), bis-ethylhexyloxyphenol methoxy--phenyltriazine (Anisotriazine or Tinosorb®S, Ciba-Geigy), 1, 1-dicarboxy (2, 2 ^{^''} - dimethyl ) -4-4-diphenyl butadiene, 2- (4-N, N-diethylamino-2-hydroxybenzoyl) benzoic acid (Uvinul®A Plus, BASF Aktiengesellschaft) and ^{2,2'-methylenebis} [6- (2H-benzotriazol -2-yl) -4- (1,1,3,3-tetramethylbutyl) phenol] (Tinosorb®M, Ciba-Geigy).

A further preferred embodiment relates to the use of a compound according to formula 1, preferably N, N-dimethyldecanamide (CAS No. 14433-76-2) (Spectrasolv DMDA, Jiangsu Feixang Chemicals), with mixtures of at least two of the abovementioned sparingly soluble UV Filter in dermocosmetics. In this case, particular preference is given to the mixtures listed under the abovementioned combinations [combination A to combination T 2].

In a particularly preferred embodiment of the present invention, the compounds according to formula I, preferably N, N-dimethyldecanamide (Spectrasolv DMDA; Jiangsu Feixang Chemicals), and the above-mentioned poorly soluble organic UV filters can be used to protect human skin or human hair against UV Radiation suitable dermocosmetics alone or combined with other absorbing in the UV range compounds, but at least effective amounts of the compounds of formula I, preferably N ₁ N-dimethyldecanamide, and the above-mentioned poorly soluble organic UV filter should be included in the sunscreen preparations , Effective amounts are generally understood as meaning in each case at least 1% by weight, based on the cosmetic preparation. Preferably, the particular use in a concentration between 0.1 to 20, preferably 1 to 15, particularly preferably 1 to 10 weight percent (% by weight) based on the total weight of the composition, wherein the amounts of the compounds according to formula I, preferably N , N-dimethyldecanamide, and the above sparingly soluble organic UV filter need not be the same.

Another object of the present invention is the combined use of the compounds of formula I, preferably N, N-dimethyldecanamide (Spectrasolv DMDA, Jiangsu Feixang Chemicals), and the above poorly soluble organic UV filter in dermocosmetics with at least one other organic or inorganic UV -Filter. In the case of the inorganic UV filters, preference is given to tandioxide, zinc oxide, iron oxide, zirconium oxide and cerium oxide, particularly preferably titanium dioxide and zinc oxide, all of the metal oxides mentioned being able to be present individually or in mixtures. In the case of the organic UV filters, the use of UV filters is selected from the group comprising 4-aminobenzoic acid derivatives, 3- (4-trimethylammonium) -benzylidene-bornan-2-one methylsulfate derivatives, 3,3,5-trimethylcyclohexyl-salicylate derivatives , 2-hydroxy-4-methoxybenzophenone derivatives, 2-phenylbenzimidazole-5-sulfonic acid derivatives and their potassium, sodium, and the like. Triethanolamine salts, 3,3 '- (1, 4-phenylenediaethyne) bis (7,7-dimethyl-2-oxobicyclo [2.2.1] heptane-1-methanesulfonic acid) derivatives and their salts, 1- (4 tert-butylphenyl) -3- (4-methoxyphenyl) propane-1,3-dione derivatives, 3- (4'-sulfo) benzylidene-bornan-2-one derivatives and their salts, 2-cyano-3,3 -diphenyl-acrylic acid (2-ethylhexyl ester) derivatives, polymer of N- [2 (and 4) - (2-oxoborn-3-ylidenemethyl) benzyl] acrylamide, 4-methoxycinnamic acid 2-ethylhexyl ester derivatives , Ethoxylated ethyl 4-aminobenzoate derivatives, 4-methoxycinnamic acid isoamyl ester derivatives, 2- (2H-benzotriazol-2-yl) -4-methyl-6- (2-methyl-3- (1, 3 , 3,3-tetramethyl-1 - (trimethylsilyloxy) -dililoxanyl) propyl) phenol derivatives, 3- (4'-methylbenzylidene) -DL-camphor derivatives, 3-benzylidene-camphor derivatives, 2-ethylhexyl salicylate Derivatives, 2-ethylhexyl 4-dimethyl-aminobenzoate derivatives, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid derivatives and their sodium salts, 2,2 ^' - (1,4-phenylene) bis (1 H-benzimidazole-4,6-disulfonic acid ure derivatives, 2,4-bis [4- (2-ethylhexyl-oxy) -2-hydroxy-phenyl] -6- (4-methoxyphenyl) -1, 3,5-triazene derivatives, dimethicodiethylbenzalmalonate derivatives and 2- (-4- (diethlyamino) -2-hydroxybenzoyl-benzoic acid hexyl ester derivatives are preferred.

In a preferred embodiment of the invention, the dermocosmetics contain the additional organic UV filters in a concentration of 0.1 to 20, preferably 1 to 15, particularly preferably 1 to 10% by weight, based on the total weight of the agent.

In a further preferred embodiment of the present invention, in addition to at least one compound according to formula 1, preferably N, N-dimethyldecanamide (Spectrasolv DMDA, Jiangsu Feixang Chemicals), and at least one sparingly soluble UV filter, as ingredients of the above-described dermocosmetics additionally at least one further inorganic filter selected from the group consisting of titanium dioxide, zinc oxide, iron oxide, zirconium oxide and cerium oxide and an organic UV filter selected from the group consisting of 4-aminobenzoic acid derivatives, 3- (4-trimethylammonium) -benzyliden-bornan-2-one methylsulfate derivatives , 3,3,5-trimethylcyclohexyl salicylate derivatives, 2-hydroxy-4-methoxybenzophenone derivatives, 2-phenylbenzimidazole-5-sulfonic acid derivatives and their potassium, sodium, and the like. triethanolamine min salts, 3,3 '- (1,4-phenylenediaethyne) bis- (7,7-dimethyl-2-oxobicyclo [2.2.1] heptane-1-methanesulfonic acid) derivatives and their salts, 1- (4 -tert.Butylphenyl) -3-

(4-methoxyphenyl) propane-1,3-dione derivatives, 3- (4'-sulfo) -benzylidene-bornan-2-one

Derivatives and its salts, 2-cyano-3,3-diphenyl-acrylic acid (2-ethylhexyl ester) derivatives, polymer of N- [2 (and 4) - (2-oxoborn-3-ylidenemethyl) benzyl] -acrylamide, 4 2-ethyl hexyl methoxy cinnamate derivatives, ethoxylated ethyl 4-amino benzoate derivatives, 4-methoxycinnamic acid isoamyl ester derivatives, 2- (2H-benzotriazol-2-yl) -4-methyl-6 (2-methyl-3- (1,3,3,3-tetramethyl-1- (trimethylsilyloxy) disiloxanyl) propyl) phenol derivatives, 3- (4'-methylbenzylidene) -DL-camphor derivatives, Benzylidene-camphor derivatives, 2-ethylhexyl salicylate derivatives, 2-ethylhexyl 4-dimethylaminobenzoate derivatives, 2-hydroxy-4-methoxy-benzophenone-5-sulfonic acid derivatives and the sodium salt, 2,2 ^' - (1,4-phenylene) bis (1H-benzimidazole-4,6-disulfonic acid derivatives, 2,4-bis [4- (2-ethylhexyl-oxy) -2-hydroxy-phenyl] -6- (4 -methoxyphenyl) -1, 3,5-triazene derivatives, dimethicodiethylbenzalmalonate derivatives and 2 - (- 4- (diethlyamino) -2-hydroxylbenzoyl-benzoic acid hexyl ester derivatives are used The use of N, N-dimethyldecanamide with at least one sparingly soluble UV filter, preferably triazine, diarylbutadiene, hydroxybenzophenone and / or methylene-bis-benzotriazolyl-tetramethylbutylphenol derivatives, particularly preferably 2,4,6- tris [anilino (p-carbo-2 ^{^'-ethyl-1'} -hexyloxy)] - 1, 3,5-triazine (Uvinul ®-T150, BASF Aktienge- roped,) Dioctylbutamido-triazone (UV-Sorb-HEB ®, 3V Sigma), bis-ethylhexyloxyphenol methoxyphenyltriazin (Anisotriazine or Tinosorb®S, Ciba-Geigy), 1, 1-dicarboxy (2 ^{^'2'} -dimethyl) -4-4-diphenyl butadiene, 2- (4-N, N-diethylamino-2-hydroxybenzoyl) benzoic acid (Uvinul® A Plus, BASF Aktiengesellschaft) and 2,2-methylenebis [6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl ) phenol] (Tinosorb®M, Ciba-Geigy), very particularly preferably 2,4,6-tris [anilino (p-carbo-2 ^{^'-ethyl-1'} - hexyloxy)] - 1, 3,5- triazine (Uvinul © -T150, BASF Aktiengesellschaft) and 2- (4-N ₁ N-diethylamino-2-hydroxybenzoyl) benzoic acid (Uvinul®A Plus, BASF Aktiengesellschaft nite), and titanium dioxide and / or zinc oxide and at least one further organic UV filter from the group consisting of 2-hydroxy-4-methoxybenzophenone derivatives, 2-cyano-3,3-diphenyl-2-ethylhexyl acrylate derivatives and ethoxylated Ethyl 4-aminobenzoate derivatives.

In another embodiment of the invention, the previously described organic or inorganic UV filters can be used in micronized form.

Another object of the invention is the use of a compound according to the general formula I, preferably N, N-dimethyldecanamide (Spectrasolv DMDA; Jiangsu Feixang Chemicals), to avoid the recrystallization of poorly soluble organic UV filters, preferably triazine, diarylbutadiene, hydroxybenzophenone and / or methylene-bis-benzotriazolyl-tetra-methylbutyl-phenol derivatives, particularly preferred 2,4,6-tris [anilino (p-carbo-2 ^{^'-ethyl-1'} -hexyloxy)] - 1, 3 , 5-triazine (Uvinul®-T150, BASF Aktiengesellschaft,) dioctylbutamido-triazone (UV-Sorb-HEB®, 3V Sigma), bis-ethylhexyloxyphenol-methoxyphenyltriazine (anisotriazines or Tinosorb®S, Ciba) Geigy), 1, 1-dicarboxy (2 ^{^'2'} -dimethyl) -4-4-diphenyl butadiene, 2- (4-N, N-diethylamino-2-hydroxybenzoyl) benzoic acid (Uvinul®A Plus, BASF Aktiengesellschaft) and 2,2-methylenebis [6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) phenol] (Tinosorb®M, Ciba-Geigy), very particularly preferably 2,4, 6-tris [anilino (p-carbo-2 ^{^'-ethyl-1'} - hexyloxy)] - 1, 3,5-triazine (Uvinul ®-T150, BASF Aktiengesellschaft) and 2- (4-N ₁ N- Diethylamino-2-hydroxybenzoyl) benzoic acid (Uvinul®A Plus, BASF Aktiengesellschaft) in dermocosmetics suitable for protection against UV radiation.

In a preferred embodiment, the use of a compound GE measured the general formula I, preferably N, N-dimethyldecanamide (Spectrasolv DMDA, Jiangsu Feixang Chemicals), to avoid the recrystallization of sparingly soluble organic UV filter in a concentration between 1 and 50, preferably from 5 to 45, more preferably from 10 to 40, most preferably from 15 to 35, especially from 20 to 30% by weight based on the total weight of Dermoksometikums used.

Another object of the invention is the use of a compound according to the general formula I, preferably N, N-dimethyldecanamide (Spectrasolv DMDA, Jiangsu Feixang Chemicals), to increase the sun protection factor of a dermatogenetic suitable for protecting the skin from UV radiation Dermoksometikums in a concentration between 0.1 to 20, preferably 1 to 15, particularly preferably 1 to 10% by weight based on the total weight of Dermoksometikums wherein.

The invention further relates to the use of a compound of the general formula I, preferably N, N-dimethyldecanamide (Spectrasolv DMDA; Jiangsu Feixang Chemicals), for increasing the solubility of organic UV filters selected from the group comprising triazine, diarylbutadiene, hydroxybenzophenone and / or methylene-bis-len benzotriazolyl tetramethylbutyl-phenol derivatives, particularly preferred 2,4,6-tris [anilino (p-carbo-2 ^{^'-ethyl-1'} -hexyloxy)] - 1, 3 , 5-triazine (Uvinul® -T150, BASF Aktiengesellschaft,) dioctylbutamido-triazone (UV-Sorb-HEB®, 3V Sigma), bis-ethylhexyloxyphenol-methoxyphenyltriazine (anisotriazines or Tinosorb®S, Ciba-Geigy), 1, 1-dicarboxy (2 ^{^'2'} -dimethyl) -4-4-diphenyl butadiene, 2- (4-N, N-diethylamino-2-hydroxybenzoyl) benzoic acid (Uvinul®A Plus, BASF Aktiengesellschaft) and 2.2 - methylenebis [6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) phenol] (Tinosorb®M, Ciba-Geigy), most preferably 2,4,6-tris [ anilino- (p-carbo-2 ^{^'-ethyl-1'} - hexyloxy)] - 1, 3,5-triazine (Uvinul © -T150, BASF Aktiengesellschaft) and 2- (4-N ₁ N-diethylamino-2-hydroxybenzoyl) benzoic acid (Uvinul®A Plus, BASF Aktiengesellschaft) in an isolated Oil component or in at least one oil phase of a dispersed two- or multi-phase system, which may additionally contain one or more water phases.

When used according to the invention, the UV filters mentioned above have an increased solubility in either an isolated oil component or in at least one an oil phase of a disperse two-phase or multiphase system which may contain one or more water phases in addition that no connection systems of the general formula I in comparison with the abovementioned oil, preferably N ₁ N- Dimethyldecanamid contain. It is preferred according to the invention to use emulsions of the O / W, W / O, W / O / W, W / Si or O / W / O type as the basis for the preparation of dermocosmetics according to the invention.

The sunscreen-containing cosmetic and pharmaceutical preparations are generally based on a carrier which contains at least one oil phase. However, preparations based on water alone are also possible when using compounds having hydrophilic substituents. Accordingly, oils, oil-in-water and water-in-oil emulsions, creams and pastes, lip balm sticks or fat-free gels are contemplated.

As emulsions u.a. also O / W macroemulsions, O / W microemulsions or O / W / O emulsions in question, wherein the emulsions by phase inversion technology, according to DE-A-197 26 121 are available.

Typical cosmetic auxiliaries which may be considered as additives are, for example, co-emulsifiers, fats and waxes, stabilizers, thickeners, biogenic active ingredients, film formers, fragrances, dyes, pearlescing agents, preservatives, pigments, electrolyte (eg magnesium sulfate) and pH. regulators. Suitable coemulsifiers are preferably known W / O and also O / W emulsifiers, such as polyglycerol esters, sorbitan esters or partially esterified glycerides. Typical examples of fats are glycerides; Beeswax, paraffin wax or microwaxes, optionally in combination with hydrophilic waxes, may be mentioned as waxes. As stabilizers metal salts of fatty acids such as magnesium, aluminum and / or zinc stearate can be used. Suitable thickeners are, for example, crosslinked polyacrylic acids and their derivatives, polysaccharides, in particular xanthan gum, guar guar, agar agar, alginates and tyloses, carboxymethylcellulose and hydroxyethylcellulose, furthermore fatty alcohols, monoglycerides and fatty acids, polyacrylates, polyvinyl alcohol and polyvinylpyrrolidone. Biogenic active ingredients are, for example, plant extracts, protein hydrolysates and vitamin complexes. Typical film formers are, for example, hydrocolloids such as chitosan, microcrystalline chitosan or quaternized chitosan, polyvinylpyrrolidone, vinylpyrrolidone-vinyl acetate copolymers, polymers of the acrylic acid series, quaternary cellulose derivatives and similar compounds. Suitable preservatives are, for example, formaldehyde solution, p-hydroxybenzoate or sorbic acid. Suitable pearlescing agents are, for example, glycol distearate esters, such as ethylene glycol distearate, but also fatty acids and fatty acid monoglycol esters. Dyes which may be used are those which are suitable and approved for cosmetic purposes, as described, for example, in the publication "Kosmetische Färbemittel" of the Dye Commission of the Deutsche Forschungsgemeinschaft, published in Verlag Chemie, Weinheim, 1984, are compiled. These dyes are usually used in concentrations of 0.001 to 0.1 wt .-%, based on the total mixture.

An additional content of antioxidants is generally preferred. Thus, all antioxidants which are suitable or customary for cosmetic and / or dermatological applications can be used as favorable antioxidants.

Advantageously, the antioxidants are selected from the group consisting of amino acids (eg, glycine, histidine, tyrosine, tryptophan) and their derivatives, imidazoles (eg, urocanic acid) and their derivatives, peptides such as D, L-carnosine, D-carnosine, L-carnosine and their derivatives (eg anserine), carotenoids, carotenes (eg .beta.-carotene, lycopene) and their derivatives, chlorogenic acid and its derivatives, lipoic acid and derivatives thereof (eg dihydrolipoic acid), aurothioglucose, propylthiouracil and other thiols (eg thiorodoxin, glutathione , Cysteine, cystine, cystamine and their glycosyl, N-acetyl, methyl, ethyl, propyl, amyl, butyl, and lauryl, palmitoyl, oleyl, α-linoleyl, cholesteryl and glyceryl esters ) as well as their salts, dilauryl thiodipropionate, distearyl thiodipropionate, thiodipropionic acid and its derivatives (esters, ethers, peptides, lipids, nucleotides, nucleosides and salts) as well as sulfoximine compounds (eg buthinine sulfoximines, homocysteine sulfoximines, buthionine sulfones, penta, hexa -, Heptathio- ninsulfoximin) in very low tolerated dosages (eg pmol to μmol / kg), furthermore (metal) chelators (eg α-hydroxy fatty acids, palmitic acid, phytic acid, lactoferrin), α-hydroxy acids (eg citric acid, lactic acid, Malic acid), humic acid, bile acids, bile extracts, biliburin, biliverdin, EDTA and their derivatives, unsaturated fatty acids and their derivatives (eg γ-linolenic acid, linoleic acid, oleic acid), folic acid and its derivatives, ubiquinone and ubiquinol and their derivatives, vitamin C and their derivatives (eg, ascorbyl palmitate, Mg ascorbyl phosphate, ascorbyl acetate), tocopherol and derivatives (eg, vitamin E acetate, tocotrienol), vitamin A and derivatives (vitamin A palmitate), as well as coniferyl benzoate of benzoin, rutinic acid and derivatives thereof, α Glycosylrutin, ferulic acid, furfurylidene glucitol, carnosine, butylhydroxytoluene, butylhydroxyanisole, nordihydroguaiacetic acid, nordihydroguiaretic acid, trihydroxybuty- rophenone, uric acid and their derivatives ate, mannose and their derivatives, zinc and its derivatives (eg ZnO, ZnSO ₄ ), selenium and its derivatives (eg selenium methionine), stilbenes and their derivatives (eg stilbene oxide, trans-stilbene oxide).

The amount of the aforementioned antioxidants (one or more compounds) in the preparations is preferably 0.001 to 30 wt .-%, particularly preferably 0.05 to 20 wt .-%, in particular 1 to 10 wt .-%, based on the total weight of Preparation.

If vitamin E and / or its derivatives represent the antioxidant (s), it is advantageous to determine their respective concentration from the range of 0.001 to 10% by weight. %, based on the total weight of the formulation.

If vitamin A and / or its derivatives or carotenoids constitute the antioxidant (s), it is advantageous to choose their respective concentration from the range from 0.001 to 10% by weight, based on the total weight of the formulation.

Typical oil components in cosmetics are, for example, paraffin oil, glyceryl stearate, isopropyl myristate, diisopropyl adipate, cetylstearyl 2-ethylhexanoate, hydrogenated polyisobutene, petrolatum, caprylic acid / capric acid triglycerides, microcrystalline wax, lanolin and stearic acid.

The total amount of auxiliaries and additives may be 1 to 80, preferably 6 to 40 wt .-% and the non-aqueous portion ("active substance") 20 to 80, preferably 30 to 70 wt .-% - based on the means - amount. The preparation of the agents can be carried out in a manner known per se, i. for example, by hot, cold, hot-hot / cold or PIT emulsification. This is a purely mechanical process, a chemical reaction does not take place.

Such sunscreen preparations may accordingly be in liquid, pasty or solid form, for example as water-in-oil creams, oil-in-water creams and lotions, aerosol foam creams, gels, oils, fatty sticks, powders, sprays or alcoholic aqueous lotions.

Finally, further substances known per se which absorb in the UV range can be used if they are stable in the overall system of the combination of UV filters to be used according to the invention.

Examples

The following examples are disclosed to illustrate preferred embodiments of the present invention. These examples are not to be considered as limiting or limiting the invention. In these examples, the preferred compound of the formula I used is the N, N-dimethyldecanamide Spectrasolv DMDA (Jiangsu Feixang Chemicals).

example 1

Example 2

Example 3

Example 4

Example 5

Example 6

Example 7

Example 8

Example 9

Solubility of Uvinul A Plus in Uvinul MC 80

Solubility of Uvinul A Plus in Octocrylene

Solubility of Uvinul T 150 in various cosmetic oils

Uvinul® T

Oil temp. 150 remarks

Type ° C weight%

Cosmacol®

EMI 20 22,94 canceled after 72h, because not completely solved

Cosmacol®

ETI 20 22,83 completely solved

25.80 canceled after 48h, because not completely solved

Cetiol CC 20 19.96 stopped after 48h, because not completely dissolved

Spectrasolv

DMD A 20 56.57 completely dissolved

Hallbrite BHB 20 20,14 canceled after 48h, because not completely solved

Silsoft 305 20 19.95 canceled after 48h, because not completely solved

Lexfeel 20 19.89 canceled after 72h, because not completely solved

Tncmaml

Claims

claims

1. Dermocosmetic suitable for protection against UV radiation, containing

a) a compound of general formula I,

O

Formula I 1 1

GH ₃ (CH ₂ ) _n -CN (CH ₃ ) ₂ where "n" corresponds to an integer from 2 to 12, and

b) at least one sparingly soluble organic UV filter.

The dermocosmetic of claim 1, wherein the sparingly soluble organic UV filter is a triazine derivative, diarylbutadiene derivative, hydroxybenzophenone derivative and / or methylene bis-benzotriazolyl tetramethylbutylphenol derivative.

3. dermocosmetic according to claim 1, wherein the compound (a) corresponds to N ₁ N-dimethyldecanamide.

4. dermocosmetic according to claim 1, wherein the sparingly soluble organic UV filters and the compound according to formula 1 are used in each case in a concentration of 0.1 to 50 weight percent based on the total weight of the dermocosmetic.

5. Dermocosmetic according to claim 1, additionally containing at least one further organic or inorganic UV filter.

6. Dermocosmetic according to claim 5, wherein the inorganic UV filter is selected from the group consisting of titanium dioxide, zinc oxide, iron oxide, zirconium oxide, cerium oxide and mixtures thereof

7. dermocosmetic according to claim 5, wherein the additional organic UV filter is selected from the group consisting of 4-aminobenzoic acid derivatives, 3- (4-trimethylammonium) -Benzyliden-bornan-2-one-methylsulfat derivatives, 3,3,5-tri methylcyclohexyl salicylate derivatives, 2-hydroxy-4-methoxybenzophenone derivatives, 2-phenylbenzimidazole-5-sulfonic acid derivatives, and their potassium, sodium, and the like; Triethanolamine salts, 3,3 '- (1,4-phenylenedienethine) bis- (7,7-dimethyl-2-oxobicyclo [2.2.1] heptane-1-methanesulfonic acid) derivatives and their salts, 1- (4-tert-butylphenyl) -3- (4-methoxyphenyl) propane-1,3-dione derivatives, 3- (4'-sulfo) -benzylidene-bornan-2-one

Derivatives and their salts, 2-cyano-3,3-diphenyl-acrylic acid (2-ethylhexyl ester) derivatives, polymer of N- [2 (and 4) - (2-oxoborn-3-ylidenemethyl) benzyl] -acrylamide, 4 - Methoxy-cinnamic acid 2-ethylhexyl ester derivatives, ethoxylated ethyl 4-aminobenzoate derivatives, 4-methoxycinnamic acid isoamyl ester derivatives, 2- (2H-benzotriazol-2-yl) -4-methyl- 6- (2-methyl-3- (1,3,3,3-tetramethyl-1- (trimethylsilyloxy) -disiloxanyl) propyl) -phenol-Deιϊvate, 3- (4'-methylbenzylidene) -DL-camphor derivatives , 3-Benzylidene camphor derivatives, 2-ethylhexyl salicylate derivatives, 2-ethylhexyl 4-dimethylaminobenzoate derivatives, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid derivatives and their derivatives Sodium salts, 2,2 ^' - (1,4-phenylene) bis (1H-benzimidazole-4,6-disulfonic acid derivatives, 2,4-bis [4- (2-ethylhexyl-oxy) -2-hydroxy-phenyl] -6- (4-methoxyphenyl) -1, 3,5-triazene derivatives, dimethicodiethylbenzalmalonate derivatives and 2 - (- 4- (diethlyamino) -2-hydroxylbenzoyl-benzoic acid hexyl ester

Derivatives.

8. The dermocosmetic according to claim 5, wherein the additional organic or inorganic UV filters are used in a concentration of between 0.1 and 50% by weight, based on the total weight of the dermocosmetic.

9. dermocosmetic according to claim 2, wherein the poorly soluble organic UV filter (b) is a triazine derivative selected from the group consisting of 2,4,6-tris [anilino- (p-carbo-2 ^' ethyl-1 ^' - hexyloxy)] - 1, 3,5-triazine, sotriazine dioctylbutamidotriazone, anilines, 2,4,6-tris (diethyl-4 ^{'-aminobenzalmalonate)} -s-triazine, 2,4,6-tris (dimethyl- 4 ^{'-amino-benzalmalonates-s-triazine,} 2,4,6-tris (diiso-propyl-4-aminobenzal- malonate) -s-triazine, 2,4,6-tris ^[3' benzotriazole-2-yl ) -2 ^{^'hydroxy-5'} -methyl) phenyl- amino] -s-triazine and 2,4,6-tris [3 ^{'benzotriazol-2-yl)} ^-2' -hydroxy-5 ^{'-tert-octyl)} phenylamino] -s-triazine.

10. Dermokosmetikum according to claim 9, wherein the triazine derivative is selected from the group consisting of 2,4,6-tris [anilino (p-carbo-2 ^{^'-ethyl-1'} -hexyloxy)] - 1, 3,5- triazine, dioctylbutamidotriazone and anisotriazine.

1 derermokosmetikum according to claim 2, wherein the Diarylbutadienderivat corresponds to a 4,4'-Diarylbutadiene of the formula II,

COOR 4

COOR5 _{τ τ}

Formula Il

wherein R ⁴ and R ⁵ are independently hydrogen, Ci-C ₂ -alkyl, C ₃ -C ₀ -

Cycloalkyl or C ₃ -C mean ₀ cycloalkenyl.

12. dermocosmetic according to claim 1 1, wherein the 4,4'-diarylbutadiene the 1, 1-dicarboxy (2 ^' 2 ^' dimethyl) -4-4-diphenyldutadien corresponds.

13. dermocosmetic according to claim 2, wherein the poorly soluble organic UV filter (b) is selected from the group comprising a hydroxybenzophenone of the general

Formula IM

wherein R ¹ and R ² are independently hydrogen, Ci-C ₂ -alkyl, C ₃ -C ₀ - cycloalkyl or C ₃ -C mean ₀ cycloalkenyl, wherein the substituents R ¹ and R ² together with the nitrogen atom to which they are bonded, can form a 5- or 6- ring and R ^{3 is} a Ci-C ₂₀ alkyl.

The dermocosmetic of claim 13, wherein the hydroxybenzophenone derivative is 2- (4-N, N-diethylamino-2-hydroxybenzoyl) benzoic acid.

15. dermocosmetic according to claim 2, wherein the sparingly soluble organic UV filter is a methylene-bis-benzotriazolyl tetramethylbutylphenolderivat.

16. dermocosmetic according to claim 15, wherein the methylene-bis-benzotriazolyl tetramethylbutylphenolderivat the 2,2 ^' -methylenbis [6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) phenol] equivalent.

17. dermocosmetic according to claim 2, comprising mixtures of the defined in claims 9 to 16 organic UV filters.

18. Dermocosmetic according to claim 1, additionally comprising at least one further inorganic filter selected from the group consisting of titanium dioxide, zinc oxide, iron oxide, zirconium oxide and cerium oxide and an organic UV filter selected from the group consisting of 4-aminobenzoic acid derivatives, 3- (4-trimethylammonium) -benzylidene -bornan-2-one-methylsulfate derivatives, 3,3,5-trimethylcyclohexyl-salicylate derivatives, 2-hydroxy-4-methoxybenzophenone derivatives, 2-

Phenylbenzimidazole-5-sulfonic acid derivatives and their potassium, sodium u. Triethanolamine salts, 3,3 '- (1, 4-phenylenediaethyne) bis- (7,7-dimethyl-2-oxobicyclo [2.2.1] -heptane-1-methanesulfonic acid) derivatives and their salts, (4-tert-butylphenyl) -3- (4methoxyphenyl) propane-1,3-dione derivatives, 3- (4'-sulfo) -benzylidene-bornan-2-one derivatives and its salts, 2-cyano-3,3-diphenyl-acrylic acid (2-ethylhexyl ester ) Derivatives, polymer of N- [2 (and 4) - (2-oxoborn-3-ylidenemethyl) benzyl] -acrylamide, 4-methoxycinnamic acid 2-ethylhexyl ester derivatives, ethoxylated ethyl 4-aminobenz - zoate derivatives, 4-methoxycinnamic acid isoamyl ester derivatives, 2- (2H-benzotriazol-2-yl) -4-methyl-6- (2-methyl-3- (1,3,3,3-tetramethyl 1- (trimethylsilyloxy) -disiloxanyl) propyl) phenol derivatives, 3- (4'-methylbenzylidene) -DL-camphor derivatives, 3-benzylidene-camphor derivatives, 2-ethylhexyl salicylate derivatives, 4-dimethyl- aminobenzoic acid 2-ethylhexyl ester derivatives, 2-hydroxy-4-methoxy-benzophenone-5-sulfonic acid derivatives and the sodium salt, 2,2 ^' - (1,4-phenylene) bis (1H-benzimidazole-4,6- disulfonic acid derivatives, 2,4-bis [4- (2-ethylhexyl-oxy) -2-hydroxy-phenyl] -6- (4-methoxyphenyl) -1, 3,5-triazene derivatives, dimethicodiethylbenzalmalonate derivatives and 2 - (- 4- (Diethlyamino) -2-H ydroxylbenzoyl-benzoic acid hexyl ester derivatives.

19. dermocosmetic according to claim 18, wherein the inorganic filter is titanium dioxide, or zinc oxide and the organic UV filter selected from the group consisting of 2-hydroxy-4-methoxybenzophenonderivate, 2-cyano-3,3-diphenyl-acrylic acid (2 ethylhexyl ester) derivatives and ethoxylated-ethyl-4-amino-benzoate derivatives.

20. Dermocosmetic according to one of the preceding claims, wherein the inorganic UV filters are present in micronized form.

21. Dermocosmetic according to one of the preceding claims, wherein the organic see UV filters in micronized form.

22. Use of a compound according to the general formula I in combination with at least one sparingly soluble organic UV filter in for the protection of human skin or human hair against UV radiation suitable dermocosmetics.

23. Use according to claim 22, wherein the compound according to formula I is N, N-dimethyldecanamide.

24. Use according to claim 22, wherein the sparingly soluble organic UV filter is a triazine derivative, diarylbutadiene derivative, hydroxybenzophenone derivative or methylene bis-benzotriazolyl tetramethylbutylphenol derivative.

25. Use according to claim 22, wherein the sparingly soluble organic UV filters and the compound according to formula 1 are each used in a concentration of between 0.1 and 20 percent by weight, based on the total weight of the dermocosmetic

26. Use according to claim 22, wherein the dermocosmetic contains at least one further organic or inorganic UV filter.

27. Use according to claim 26, wherein inorganic UV filter is selected from the group consisting of titanium dioxide, zinc oxide, iron oxide, zirconium oxide, cerium oxide and mixtures thereof.

28. Use according to claim 26, wherein the additional organic UV filter is selected from the group comprising 4-aminobenzoic acid derivatives,

(4-trimethylammonium) -benzyliden-bornan-2-one-methylsulfate derivatives, 3,3,5-trimethylcyclohexyl-salicylate derivatives, 2-hydroxy-4-methoxybenzophenone derivatives, 2-phenylbenzimidazole-5-sulfonic acid derivatives and their potassium -, sodium u. Triethanolamine salts, 3,3 '- (1,4-phenylenedienethine) bis- (7,7-dimethyl-2-oxobicyclo [2.2.1] heptane-1-methanesulfonic acid) derivatives and their salts, 1- (4-tert-butylphenyl) -3-

(4methoxyphenyl) propane-1,3-dione derivatives, 3- (4'-sulfo) -benzylidene-bornan-2-one derivatives and their salts, 2-cyano-3,3-diphenyl-acrylic acid (2-ethylhexyl ester ) Derivatives, polymer of N- [2 (and 4) - (2-oxoborn-3-ylidenemethyl) benzyl] -acrylamide, 4-methoxycinnamic acid 2-ethylhexyl ester derivatives, ethoxylated ethyl 4-aminobenz - zoate derivatives, 4-methoxycinnamic acid isoamyl ester derivatives, 2- (2H-benzotriazol-2-yl) -4-methyl-6- (2-methyl-3- (1,3,3,3-tetramethyl -1- (trimethylsilyloxy) disiloxanyl) propyl) phenol derivatives, 3- (4'-methylbenzylidene) -DL camphor derivatives, 3-benzylidene camphor derivatives, 2-ethylhexyl salicylate derivatives, 4- Dimethylaminobenzoic acid 2-ethylhexyl ester derivatives, 2-hydroxy-4-methoxy-benzophenone-5-sulfonic acid derivatives and their sodium salts, 2,2 ^' - (1, 4-

Phenylene) bis (1H-benzimidazole-4,6-disulfonic acid derivatives, 2,4-bis [4- (2-ethylhexyloxy) -2-hydroxy-phenyl] -6- (4-methoxyphenyl) -1,3 , 5-triazene derivatives, dimethico-diethylbenzalmalonate derivatives and 2 - (- 4- (diethlyamino) -2-hydroxylbenzoyl-benzoic acid hexyl ester derivatives.

29. Use according to claim 26, wherein the additional organic or inorganic UV filters are used in a concentration of between 0.1 and 50% by weight, based on the total weight of the dermocosmetic.

30. Use according to claim 24, wherein the triazine derivative is selected from the group consisting of 2,4,6-tris [anilino (p-carbo-2 ^{^'-ethyl-1'} -hexyloxy)] - 1, 3,5- triazine, dioctyl, Anisotriazin, 2,4,6-tris (diethyl-4 ^{'-aminobenzalmalonate)} -s-triazine, 2,4,6-tris ^(dimethyl-4' -amino-benzalmalonates-s-triazine, 2,4 , 6-tris (diisopropyl propyl-4-aminobenzalmalonate) -s-triazine, 2,4,6-tris [3 ^{'benzotriazole-2-yl)} ^-2' - hydroxy-5 ^'methyl) phenyl-amino] -s-triazine and 2,4,6-tris [3 ^{'benzotriazol-2-yl)} ^-2' - hydroxy-5 ^'tert-octyl) phenylamino] -s-triazine.

31. Use according to claim 30, wherein the triazine derivative is selected from the group consisting of 2,4,6-tris [anilino (p-carbo-2 ^{^'-ethyl-1'} -hexyloxy)] - 1, 3,5- triazine, dioctylbutamidotriazone and anisotriazine.

32. The use according to claim 24, wherein the diarylbutadiene derivative corresponds to a 4,4'-diarylbutadiene of the formula II where R ⁴ and R ⁵ independently of one another are hydrogen, C 1 -C 20 -alkyl, C 3 -C 10 -cycloalkyl or C 3 -C 10 -cycloalkenyl ,

33. Use according to claim 32, wherein the 4,4'-diarylbutadiene the 1, 1-dicarboxy (2 ^{^'2'} -dimethyl) -4-4-diphenyldutadien corresponds.

34. Use according to claim 24, wherein the sparingly soluble organic UV filter (b) corresponds to a hydroxybenzophenone of the general formula IM, where R ¹ and R ² independently of one another are hydrogen, C 1 -C 20 -alkyl, C 3 -C 10 -cycloalkyl or C 3 -C 10 -alkyl -Cycloalkenyl, wherein the substituents R ¹ and R ² together with the nitrogen atom to which they are attached, can form a 5- or 6-membered ring and R ^{3 is} a Ci-C2o-alkyl.

Use according to claim 34, wherein the hydroxybenzophenone derivative is 2- (4-N, N-diethylamino-2-hydroxybenzoyl) benzoic acid.

Use according to claim 24, wherein the sparingly soluble organic UV filter is a methylene-bis-benzotriazolyl tetramethylbutylphenol derivative.

37. Use according to claim 36, wherein said methylene-bis-benzotriazolyl Tetramethylbutylphenolderivat the ^{2,2'-methylenebis} [6- (2H-benzotriazol-2-yl) -4- (1, 1, 3,3- tetramethylbutyl) phenol] equivalent.

38. Use according to claim 24, comprising mixtures of the organic UV filters defined in claims 30 to 37.

39. Use according to claim 22, additionally comprising at least one further inorganic filter selected from the group consisting of titanium dioxide, zinc oxide, iron oxide, zirconium oxide and cerium oxide and an organic UV filter selected from the group comprising 4-aminobenzoic acid derivatives,

(4methoxyphenyl) propane-1,3-dione derivatives, 3- (4'-sulfo) -benzylidene-bornan-2-one derivatives and their salts, 2-cyano-3,3-diphenyl-acrylic acid (2-ethylhexyl ester ) - Derivatives, polymer of N- [2 (and 4) - (2-oxoborn-3-ylidenemethyl) benzyl] acrylamide, 4-methoxycinnamic acid 2-ethylhexyl ester derivatives, ethoxylated ethyl 4-aminobenzoate Derivatives, 4-methoxycinnamic acid isoamyl ester derivatives, 2- (2H-benzotriazol-2-yl) -4-methyl-6- (2-methyl-3- (1, 3,3,3-tetramethyl-1 (trimethylsilyloxy) -disiloxanyl) propyl) phenol derivatives, 3- (4'-methylbenzylidene) -DL-camphor derivatives, 3-benzylidene-camphor derivatives, 2-ethylhexyl salicylate derivatives, 4-dimethyl- aminobenzoic acid 2-ethylhexyl ester derivatives, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid derivatives and their sodium salts, 2,2 ^' - (1, 4-phenylene) bis (1H-benzimidazole) 4,6-disulfonic acid derivatives, 2,4-bis [4- (2-ethylhexyl-oxy) -2-hydroxy-phenyl] -6- (4-methoxyphenyl) -1, 3,5-triazene derivatives, dimethicodiethylbenzalmalo- nate derivatives and 2 - (- 4- (diethlyamino) -2-hydroxylbenzoyl-benzoesäurhexylester- derivatives.

40. Use according to claim 39, wherein the inorganic filter is titanium dioxide, or zinc oxide and the organic UV filter is selected from the group comprising 2-hydroxy-4-methoxybenzophenone derivatives, 2-cyano-3,3-diphenyl-acrylic acid (2 ethylhexyl ester) derivatives and ethoxylated-ethyl-4-amino benzoate derivatives.

41. Use according to any one of claims 22 to 40, wherein the organic UV filters are in micronized form.

42. Use according to any one of claims 22 to 40, wherein the inorganic UV filters are present in micronized form.

43. Use of a compound according to the general formula I for preventing the recrystallization of poorly soluble organic UV filters in dermocosmetics for protection against UV radiation.

44. Use according to claim 43, wherein the compound according to formula I is N, N-dimethyldecanamide.

45. Use according to claim 43, wherein the sparingly soluble organic UV filter is selected from the group consisting of triazine derivatives, Diarylbutadienderivate, amino-substituted Hydroxybenzophenonderivate and methylene-bis-benzotriazolyl - tetramethylbutylphenolderivate.

46. Use according to claim 45, wherein the sparingly soluble organic UV filters and the compound according to formula 1 are each used in a concentration between 0.1 and 20 percent by weight based on the total weight of the dermocosmetic.

47. Use of a compound according to the general formula I for increasing the sun protection factor of a dermatogenetic suitable for protecting the skin from UV radiation Dermoksometikums.

48. Use according to claim 47, wherein the compound of formula I are used in a concentration between 0.1 and 20 percent by weight based on the total weight of the dermocosmetic.

49. Use according to claim 47, wherein the compound according to formula 1 is N, N-dimethyldecanamide.

50. Use of a compound of the general formula I for increasing the solubility of organic UV filters selected from the group comprising triazine derivatives, diarylbutadiene derivatives, hydroxybenzophenone derivatives and methylene-bis-benzotriazolyl tetramethylbutylphenol derivatives in a) an isolated oil component or b) in at least one oil phase disperse two- or multi-phase system which may additionally contain one or more water phases.