WO2010010394A3 - Local pharmaceutical compositions comprising an extract of spilanthes - Google Patents

Local pharmaceutical compositions comprising an extract of spilanthes Download PDF

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Publication number
WO2010010394A3
WO2010010394A3 PCT/GB2009/050905 GB2009050905W WO2010010394A3 WO 2010010394 A3 WO2010010394 A3 WO 2010010394A3 GB 2009050905 W GB2009050905 W GB 2009050905W WO 2010010394 A3 WO2010010394 A3 WO 2010010394A3
Authority
WO
WIPO (PCT)
Prior art keywords
extract
spilanthes
pharmaceutical compositions
composition
need
Prior art date
Application number
PCT/GB2009/050905
Other languages
French (fr)
Other versions
WO2010010394A2 (en
Inventor
Iain Chessell
Mark Treherne
Fei-Yue Zhao
Francoise Barbira Freedman
David Spanswick
Kevin Lee
Original Assignee
Neurosolutions Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0813395A external-priority patent/GB0813395D0/en
Priority claimed from GB0908970A external-priority patent/GB0908970D0/en
Application filed by Neurosolutions Ltd filed Critical Neurosolutions Ltd
Publication of WO2010010394A2 publication Critical patent/WO2010010394A2/en
Publication of WO2010010394A3 publication Critical patent/WO2010010394A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Abstract

The present invention provides a composition adapted to supply locally to the site of need in a patient in need thereof a compound having a pharmaceutical activity, wherein the active agent of said composition comprises an extract of Spilanthes oleracea. The composition is of particular use, for example, as an analgesic in providing rapid treatment of neuropathic pain and as a long-lasting anaesthetic. Compositions of the invention for buccal admininistration can preferably be in the form of lozenges, tablets or mucoadhesive gels.
PCT/GB2009/050905 2008-07-22 2009-07-22 Local pharmaceutical compositions WO2010010394A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0813395A GB0813395D0 (en) 2008-07-22 2008-07-22 Local pharmaceutical compositions
GB0813395.1 2008-07-22
GB0908970A GB0908970D0 (en) 2009-05-26 2009-05-26 Local pharmaceutical compositions
GB0908970.7 2009-05-26

Publications (2)

Publication Number Publication Date
WO2010010394A2 WO2010010394A2 (en) 2010-01-28
WO2010010394A3 true WO2010010394A3 (en) 2010-03-18

Family

ID=41479393

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2009/050905 WO2010010394A2 (en) 2008-07-22 2009-07-22 Local pharmaceutical compositions

Country Status (1)

Country Link
WO (1) WO2010010394A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9877929B2 (en) 2011-10-13 2018-01-30 Premier Dental Products Company Topical vitamin D and ubiquinol oral supplement compositions
US9724542B2 (en) 2012-10-12 2017-08-08 Premier Dental Products Company Remineralizing and desensitizing compositions, treatments and methods of manufacture
US9877930B2 (en) * 2012-10-12 2018-01-30 Premier Dental Products Company Topical ubiquinol oral supplement compositions with amorphous calcium phosphate
JP6278417B2 (en) * 2012-10-12 2018-02-14 プレミア デンタル プロダクツ カンパニー Topical oral supplement composition of vitamin D and ubiquinol
US9522168B2 (en) 2014-05-29 2016-12-20 Johnson & Johnson Consumer Inc. Topical compositions comprising Acmella oleracea extracts and uses thereof
EP3678658A4 (en) 2017-09-08 2021-05-05 Scicann Therapeutics Inc. Compositions comprising a cannabinoid and spilanthol

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3720762A (en) * 1970-07-11 1973-03-13 Lion Hamigaki Kk Spilanthol-containing compositions for oral use
US20020122778A1 (en) * 2000-12-15 2002-09-05 Philip Wolfson Herbal composition for improving oral hygiene, for providing local anesthesia, for use as an oral sensate, flavor enhancer and potentiator, and methods of using same
JP2004189660A (en) * 2002-12-10 2004-07-08 Hayashibara Biochem Lab Inc External preparation for skin and application thereof
US20060141064A1 (en) * 2004-12-28 2006-06-29 Council Of Scientific & Industrial Research Herbal formulation useful as local anesthetic

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3720762A (en) * 1970-07-11 1973-03-13 Lion Hamigaki Kk Spilanthol-containing compositions for oral use
US20020122778A1 (en) * 2000-12-15 2002-09-05 Philip Wolfson Herbal composition for improving oral hygiene, for providing local anesthesia, for use as an oral sensate, flavor enhancer and potentiator, and methods of using same
JP2004189660A (en) * 2002-12-10 2004-07-08 Hayashibara Biochem Lab Inc External preparation for skin and application thereof
US20060141064A1 (en) * 2004-12-28 2006-06-29 Council Of Scientific & Industrial Research Herbal formulation useful as local anesthetic

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHAKRABORTY A ET AL: "LOCAL ANAESTHETIC EFFECT OF SPILANTHES ACMELLA IN EXPERIMENTAL ANIMAL MODELS", INDIAN JOURNAL OF PHARMACOLOGY, MEDKNOW PUBLICATIONS AND MEDIA PVT. LTD, IN, vol. 34, no. 2, 1 April 2002 (2002-04-01), pages 144/145, XP009035381, ISSN: 0253-7613 *
DATABASE WPI Week 200940, Derwent World Patents Index; AN 2009-K39223, XP002562927 *

Also Published As

Publication number Publication date
WO2010010394A2 (en) 2010-01-28

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