WO2012030309A3 - Formulation of comprising tiotropium and a calcium channel blocker - Google Patents

Formulation of comprising tiotropium and a calcium channel blocker Download PDF

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Publication number
WO2012030309A3
WO2012030309A3 PCT/TR2011/000199 TR2011000199W WO2012030309A3 WO 2012030309 A3 WO2012030309 A3 WO 2012030309A3 TR 2011000199 W TR2011000199 W TR 2011000199W WO 2012030309 A3 WO2012030309 A3 WO 2012030309A3
Authority
WO
WIPO (PCT)
Prior art keywords
tiotropium
calcium channel
channel blocker
formulation
copd
Prior art date
Application number
PCT/TR2011/000199
Other languages
French (fr)
Other versions
WO2012030309A2 (en
Inventor
Mahmut Bilgic
Original Assignee
Mahmut Bilgic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mahmut Bilgic filed Critical Mahmut Bilgic
Priority to EP11767092.7A priority Critical patent/EP2611447A2/en
Publication of WO2012030309A2 publication Critical patent/WO2012030309A2/en
Publication of WO2012030309A3 publication Critical patent/WO2012030309A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Abstract

The present invention relates to a dry powder formulation comprising at least one calcium channel blocker and tiotropium developed in order to be used in respiratory tract diseases such as asthma and COPD.
PCT/TR2011/000199 2010-09-01 2011-08-24 Formulation of calcium channel blocker WO2012030309A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP11767092.7A EP2611447A2 (en) 2010-09-01 2011-08-24 Formulation of comprising tiotropium and a calcium channel blocker

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2010/07251 2010-09-01
TR2010/07251A TR201007251A2 (en) 2010-09-01 2010-09-01 Calcium channel blocker formulation.

Publications (2)

Publication Number Publication Date
WO2012030309A2 WO2012030309A2 (en) 2012-03-08
WO2012030309A3 true WO2012030309A3 (en) 2012-08-09

Family

ID=44764205

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2011/000199 WO2012030309A2 (en) 2010-09-01 2011-08-24 Formulation of calcium channel blocker

Country Status (3)

Country Link
EP (1) EP2611447A2 (en)
TR (1) TR201007251A2 (en)
WO (1) WO2012030309A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2543470T3 (en) * 2009-09-30 2015-08-19 Microdose Therapeutx, Inc. Methods and compositions for the treatment of Raynaud's phenomenon
JP6092015B2 (en) * 2013-06-19 2017-03-08 日本碍子株式会社 Method for producing single crystal

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR890004691B1 (en) * 1985-07-02 1989-11-25 키 파마슈티칼스, 인코포레이티드 Composition for the treatment of chronic obstructive pulmonary disease
US20020106332A1 (en) * 2000-10-12 2002-08-08 Michael Walz Process for preparing powder formulations
US20020110529A1 (en) * 2000-10-12 2002-08-15 Karoline Bechtold-Peters Inhalable powder containing tiotropium
US20030018019A1 (en) * 2001-06-23 2003-01-23 Boehringer Ingelheim Pharma Kg Pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics
WO2003088944A1 (en) * 2002-04-13 2003-10-30 Glaxo Group Limited Dry powder inhalant composition
WO2008152398A2 (en) * 2007-06-14 2008-12-18 Cipla Limited Formulations for inhalation
US20090088408A1 (en) * 2001-06-23 2009-04-02 Meade Christopher J M Pharmaceutical compositions on anticholinergics, corticosteroids and betamimetics

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1680324A (en) 2000-05-30 2005-10-12 奥索-麦克尼尔药品公司 Dihydropyridine soft drugs, and related compositions and methods

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR890004691B1 (en) * 1985-07-02 1989-11-25 키 파마슈티칼스, 인코포레이티드 Composition for the treatment of chronic obstructive pulmonary disease
US20020106332A1 (en) * 2000-10-12 2002-08-08 Michael Walz Process for preparing powder formulations
US20020110529A1 (en) * 2000-10-12 2002-08-15 Karoline Bechtold-Peters Inhalable powder containing tiotropium
US20030018019A1 (en) * 2001-06-23 2003-01-23 Boehringer Ingelheim Pharma Kg Pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics
US20090088408A1 (en) * 2001-06-23 2009-04-02 Meade Christopher J M Pharmaceutical compositions on anticholinergics, corticosteroids and betamimetics
WO2003088944A1 (en) * 2002-04-13 2003-10-30 Glaxo Group Limited Dry powder inhalant composition
WO2008152398A2 (en) * 2007-06-14 2008-12-18 Cipla Limited Formulations for inhalation

Also Published As

Publication number Publication date
EP2611447A2 (en) 2013-07-10
TR201007251A2 (en) 2012-03-21
WO2012030309A2 (en) 2012-03-08

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